14 July 2020. New technology is offered by the Finnish Node – label-free CARS microscopy

The Finnish Advanced Light Microscopy Node is now offering Coherent Anti-Stokes Raman Scattering (CARS) microscopy.

CARS microscopy is one of the label-free multiphoton imaging techniques. It allows for chemically specific imaging of biological materials without use of fluorescent labels. CARS has been proven useful in some very specific application fields. The CARS technique is particularly well suited for high-resolution label-free imaging of lipids due to the high concentration of carbon-hydrogen bonds in the lipid material. Lipid imaging has been applied to a great variety of samples including lipid droplets in fixed and live cell cultures, various tissue sections, and even small animals in vivo (e.g. zebrafish).

In pharmaceutical applications, CARS microscopy is gaining more and more interest. Applications include visualization of chemical component distribution in dosage forms and drug carriers, dissolution and release, solid-state transformations during dissolution, and drug delivery into cells and tissues.

You can apply to use CARS microscopy at Euro-BioImaging Web Portal.

8 June 2020. Finnish Node chaired a remote access session in 2nd Euro-BioImaging Nodes meeting

2nd Euro-BioImaging Nodes meeting took place on 8 June 2020 with participants from Euro-BioImaging Nodes attending presentations and participating in discussions. This meeting took place virtually due to ongoing COVID-19 pandemic.

The Finnish Node was chairing virtual access session where members of the Finnish Node presented their experiences with virtual microscopy and remote access. This session was the most popular of the three sessions during this 2nd Euro-BioImaging Nodes meeting.

5 June 2020. Remote 3D Electron Microscopy and CLEM projects at the Finnish Node

At the Finnish Node, remote access services include remote access to microscopes and image analysis workstations, virtual microscopy where a remote user joins an operator via video call, and a possibility to send samples to one of the imaging core facilities within the Finnish Node where staff perform the imaging. All of these services are possible due to ongoing developments at the Finnish Node.

Eija Jokitalo, the head of Electron Microscopy Unit, at the University of Helsinki presented how imaging projects that require either 3D Electron Microscopy or CLEM (Correlative Light and Electron Microscopy) are conducted at her facility with remote users sending samples at Euro-BioImaging weekly meeting.

For more information about the 3D Electron Microscopy and CLEM projects, you are welcome to read this article posted on Euro-BioImaging.

8 May 2020. Finnish Node presents virtual microscopy at Euro-BioImaging weekly meeting

Remote access allows researchers to access instruments and analysis workstations remotely, for example, from the confines of their homes. The effects of COVID-19 pandemic, namely the temporary closure of core facilities in most of the countries or significant reduction in their activities, have accelerated the development of remote access services also at the Finnish Node.

An example of remote access service being developed by the Finnish Node is virtual microscopy. It consists of an operator, generally a staff member of a core facility or an experienced researcher, acquiring image data using a microscope. A remote user joins via video call to guide an operator to image particular regions of interests.

The Finnish Node presented its developments in the field of virtual microscopy at Euro-BioImaging weekly meeting on 8 May 2020. You can check a demonstration of a virtual microscopy in a short video below.

A short video segment taken from 1-hour imaging session where two remote users joined the imaging session.

For more information about the virtual microscopy, you are welcome to read this article posted on Euro-BioImaging.

15 April 2020. NordForsk funding granted to Norway, Sweden, Finland, Denmark, and Iceland

NordForsk (www.nordforsk.org), an organization that facilitates research cooperation and infrastructure development in Nordic countries, has granted Bridging Nordic Microscopy Infrastructure a total of 2.5 Million NOK for 3 years. The participating countries in this consortium are Norway (coordinating Hub), Sweden, Finland, Denmark and Iceland.

Bridging Nordic Microscopy Infrastructure (BNMI) is a network of national imaging infrastructures offering open access to biological imaging technologies in participating Nordic countries. BNMI partners include Norwegian Molecular Imaging Consortium (NorMIC) and Norwegian Advanced Light Microscopy Imaging Network (NALMIN), National Microscopy Infrastructure (NMI) in Sweden, Finnish Advanced Light Microscopy Node (FiALM), Danish BioImaging (DBI) Network and BioMedical Center of University of Iceland (BMC-UI).

The funding will be used to strengthen international competitiveness and facilitate the development of world-leading Nordic advanced microscopy environments by supporting several levels of training, from electron and light microscopy to image analysis. Training will be delivered via scientific and technical symposia, workshops, courses and knowledge exchange seminars. BNMI plans to attract talented researchers and staff of imaging facilities to Nordic countries by coordinating two mobility programs: A job shadowing program for facility staff will facilitate the exchange of experience and sharing of ideas. A short-term scientific program for PhD students and early career investigators will see researchers stay at their destination of choice in a Nordic country for up to 2 weeks.

Dissemination and outreach will be done by organizing open days and being active on social media as well as the BNMI website. Symposia and workshops will also be used as platforms for disseminating breakthroughs in emerging imaging technologies and fostering collaborations. All participating countries have already established infrastructures and network organizations at the national level that provide a full spectrum of biological imaging tools easily accessible for both the academic sector and industry. These are also united under the Euro-Bioimaging European Research Infrastructure Consortium leading the whole of Europe to work toward excellence in research.

28 January 2020. Philip Hockberger, Associate Vice President of Research at Northwestern University visits Turku Bioscience

Philip Hockberger, Associate Vice President of Research at Northwestern University in Chicago, USA has visited Turku Bioscience research center in Turku.

Philip Hockberger delivers a talk focused on careers in core facilities.

As part of his visit, Philip Hockberger toured Turku Bioscience core facilities and met with directors of core facilities. In addition, Philip Hockberger delivered two exciting talks: Career Development in Core Facilities on 28th of January and Building a Sustainable Portfolio of Core Facilities on 29th of January. His talks were attended by a wide audience from Turku Bioscience, Turku PET Centre, Laboratory of Electron Microscopy, and researchers from University of Turku and Åbo Akademi.